PRODUCT DETAILS

About Ace-Proxyvon CR Tablet

ACECLOFENAC+RABEPRAZOLE belongs to a class of non-steroidal anti-inflammatory drugs used to reduce pain and swelling in the joints conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (pain and stiffness in the backbone). Besides this, it is also used to relieve pain in the lower back, ear, tooth, and throat Arthritis causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time. The arthritis symptoms include joint pain, stiffness, redness, tenderness, swelling in and around joints, and reduced movement of joints.

ACECLOFENAC+RABEPRAZOLE is a combination of two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac belongs to a group of pain killers that works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body involved in the production of certain chemical substances (prostaglandins) that cause pain and swelling. This reduces mild to moderate pain and inflammation at the injured or damaged site decreasing stiffness in joints. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine, that belongs to a group of proton pump inhibitors that reduce the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Aceclofenac alone.

Take ACECLOFENAC+RABEPRAZOLE as prescribed by your doctor. You are advised to take ACECLOFENAC+RABEPRAZOLE for as long as your doctor has prescribed it for you based on your medical condition. You may experience indigestion, stomach pain, constipation, dizziness, nausea, and diarrhea in some cases. Most of these side effects of ACECLOFENAC+RABEPRAZOLE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before using ACECLOFENAC+RABEPRAZOLE. This medicine can increase your risk of fatal heart attack or stroke, so, if you have had any recent heart surgery, do not use ACECLOFENAC+RABEPRAZOLE. To treat your condition effectually, continue taking ACECLOFENAC+RABEPRAZOLE for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. ACECLOFENAC+RABEPRAZOLE causes drowsiness and dizziness, so drive with caution. ACECLOFENAC+RABEPRAZOLE should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol, and ACECLOFENAC+RABEPRAZOLE as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. 

Uses of Ace-Proxyvon CR Tablet

Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis

Medicinal Benefits of Ace-Proxyvon CR Tablet

ACECLOFENAC+RABEPRAZOLE is a combination of two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac belongs to the class of non-steroidal anti-inflammatory drugs (pain killers) that block the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). Prostaglandins play an important role in controlling pain and inflammation. By blocking the effect of COX enzymes, lesser PGs are produced. Thereby, it helps relieve pain and swelling associated with different types of arthritis such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (pain and stiffness in the backbone). On the other hand, Rabeprazole belongs to proton pump inhibitors (PPIs) that help reduce the excess amount of stomach acid and bile produced. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine that reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination is superior as it helps alleviate pain with minimal gastric irritation caused due to Aceclofenac alone. ACECLOFENAC+RABEPRAZOLE also used to relieve toothache, lower back pain, ear pain and throat pain. 

Directions for Use

Tablet/capsule: Take ACECLOFENAC+RABEPRAZOLE with food as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew, or break the tablet/capsule. Take ACECLOFENAC+RABEPRAZOLE exactly as prescribed by your doctor. ACECLOFENAC+RABEPRAZOLE should not be taken unless prescribed by a doctor. Based on your medical condition, your doctor will advise for how long you need to take ACECLOFENAC+RABEPRAZOLE.

Side Effects of Ace-Proxyvon CR Tablet

• Indigestion
• Stomach pain
• Constipation
• Dizziness
• Nausea
• Diarrhea

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take ACECLOFENAC+RABEPRAZOLE if you are allergic to ACECLOFENAC+RABEPRAZOLE, have severe heart failure, suffered bleeding problems (such as bleeding from the stomach or bowels while taking any pain killers), or have liver or kidney problems, have suffered bleeding problems and clotting problems. Inform your doctor before taking ACECLOFENAC+RABEPRAZOLE if you have or had disorders of the stomach, blood circulation problems to the brain, asthma, porphyria (a disorder in the formation of red blood pigment), diabetes, high blood pressure, systemic lupus erythematosus (an autoimmune condition that causes joint pain, fever and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhea, bowel pain, vomiting, and weight loss); if you are recovering from major surgery or if you are elderly. Do not take ACECLOFENAC+RABEPRAZOLE if you are pregnant or breastfeeding unless prescribed. ACECLOFENAC+RABEPRAZOLE contains Aceclofenac which should not be used during the last three months of pregnancy. ACECLOFENAC+RABEPRAZOLE may be excreted in breastmilk. Therefore, avoid breastfeeding and consult a doctor. ACECLOFENAC+RABEPRAZOLE should not be given to children as safety has not been established. ACECLOFENAC+RABEPRAZOLE can cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with ACECLOFENAC+RABEPRAZOLE as it could lead to increased drowsiness and may increase the risk of stomach bleeding. Do not take any other NSAIDs for pain relief along with ACECLOFENAC+RABEPRAZOLE unless prescribed. Prolonged intake of PPIs or proton pump inhibitors like Rabeprazole may cause brittle bones so intake of Vitamin D and calcium can be additionally given by your doctor while using ACECLOFENAC+RABEPRAZOLE. 

Drug Interactions

Drug-Drug Interaction:

ACECLOFENAC+RABEPRAZOLE interacts with other painkillers (aspirin, ibuprofen, acetaminophen, oxycodone, tramadol, naproxen, celecoxib, etoricoxib), blood thinners (clopidogrel, heparin, warfarin), medicines used to treat heart diseases (digoxin), diuretics (furosemide, amiloride), antibiotics (ciprofloxacin, norfloxacin, moxifloxacin, ciprofloxacin, ofloxacin, levofloxacin), antihypertensive (enalapril, valsartan, telmisartan, losartan, candesartan, propranolol, enalapril, lisinopril, methyldopa, clonidine, moxonidine), antidiabetics (glibenclamide, gliclazide, tolbutamide), antidepressants (fluvoxamine, paroxetine, citalopram, escitalopram, sertraline, fluoxetine), steroids (hydrocortisone, prednisolone), immunosuppressants (ciclosporin, tacrolimus), anti-HIV (zidovudine).

Drug-Disease Interaction:

ACECLOFENAC+RABEPRAZOLE may have interactions with asthma, heart, liver, and kidney problems, low vitamin B12 (anemia), high blood pressure, high cholesterol, systemic lupus erythematosus (an autoimmune condition that causes joint pain, fever and skin rashes), porphyria (a disorder in the formation of red blood pigment), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhea, bowel pain, vomiting, and weight loss).

Safety Advice

ALCOHOL

You are recommended to avoid alcohol consumption while taking ACECLOFENAC+RABEPRAZOLE. Alcohol intake along ACECLOFENAC+RABEPRAZOLE may cause increased drowsiness and drowsiness. It may also increase the risk of stomach bleeding. Please consult your doctor if you have any concerns regarding this.

PREGNANCY

ACECLOFENAC+RABEPRAZOLE is a Category C pregnancy drug and is not recommended for pregnant women, especially in the third trimester as it may cause adverse effects on the baby. However, please consult a doctor if you are pregnant or planning for pregnancy before taking ACECLOFENAC+RABEPRAZOLE.

BREAST FEEDING

Avoid breastfeeding while taking ACECLOFENAC+RABEPRAZOLE as it may be excreted in breast milk and cause adverse effects on the baby. Please consult a doctor if you are breastfeeding.

DRIVING

ACECLOFENAC+RABEPRAZOLE may cause drowsiness, dizziness, or abnormal vision. Do not drive or operate heavy machinery if you feel dizzy or drowsy.

LIVER

Dose adjustment may be needed in patients with severe liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Take ACECLOFENAC+RABEPRAZOLE with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking ACECLOFENAC+RABEPRAZOLE if you have severe kidney disease.