PRODUCT DETAILS

About Alpa M Oral Suspension

MEFENAMIC ACID+TIZANIDINE belongs to a group of NSAID (Non-Steroidal Anti-Inflammatory Drug) medicines used to provide relief from abdominal cramps caused before and during the menstrual cycle. Abdominal cramps are the throbbing pains that occur in the lower abdomen due to the menstrual cycle every month in females. In some females, the pain and discomfort caused due to menstruation are so severe that they have to take some medicine to lower pain intensity.

Uses of Alpa M Oral Suspension

Abdominal cramps caused due to menstrual cycle

Medicinal Benefits of Alpa M Oral Suspension

MEFENAMIC ACID+TIZANIDINE is a combination drug that contains 'mefenamic acid' and 'Tizanidine.' Mefenamic acid belongs to a group of medicines called NSAID (Non-Steroidal Anti-Inflammatory Drug) used to provide relief from mild to moderate pain associated with period pain, symptoms of premenstrual syndrome (PMS), and management of excessively heavy periods. MEFENAMIC ACID+TIZANIDINE works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.  Tizanidine works in the centres of the spinal cord and brain. This helps relax the muscles of the intestine or stomach and hence stops muscle contractions. Collectively, both of them help to relieve pain, bloating, cramps and discomfort caused.

Directions for Use

Take MEFENAMIC ACID+TIZANIDINE as prescribed by your doctor. Swallow whole with a glass of water. Do not crush, chew or break it. Preferably take it with food to avoid upsetting the stomach.

Side Effects of Alpa M Oral Suspension

• Abdominal pain 
• Nausea 
• Vomiting 
• Diarrhea 
• Indigestion
• Heartburn
• Weakness
  • Dryness in the mouth

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to MEFENAMIC ACID+TIZANIDINE or any other medicines, please tell your doctor. MEFENAMIC ACID+TIZANIDINE can increase the risk of fatal heart attack or stroke, gastrointestinal bleeding, ulceration, and perforation of the stomach and intestines. Do not take MEFENAMIC ACID+TIZANIDINE if you are pregnant or breastfeeding unless prescribed by the doctor. MEFENAMIC ACID+TIZANIDINE may cause drowsiness and dizziness, so drive with caution. MEFENAMIC ACID+TIZANIDINE should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol and MEFENAMIC ACID+TIZANIDINE as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Do not take other pain killers along with MEFENAMIC ACID+TIZANIDINE unless prescribed by the doctor. Keep your doctor informed about your health condition and medicines to rule out any side-effects. Avoid taking MEFENAMIC ACID+TIZANIDINE with fluvoxamine and ciprofloxacin as it may cause adverse effects such as slurred speech, dizziness, weakness, confusion, low blood pressure, or drowsiness. You are advised not to take more than 3 doses of MEFENAMIC ACID+TIZANIDINE in a single day as too much of MEFENAMIC ACID+TIZANIDINE may cause liver damage. If you have low blood pressure, liver or kidney diseases, inform your doctor before taking MEFENAMIC ACID+TIZANIDINE.

Drug Interactions

Drug-Drug Interaction:

MEFENAMIC ACID+TIZANIDINE may have interaction with pain killers (aspirin, ibuprofen, celecoxib, diclofenac, naproxen), anti-gout (probenecid), immunosuppressants (cyclosporine, tacrolimus), anticoagulants (warfarin, heparin), anti-rheumatoid (methotrexate), anti-HIV (zidovudine), anti-depressant (duloxetine, lithium, fluoxetine, sertraline), steroid medication (mifepristone), anti-allergic drugs (diphenhydramine, cetirizine), an anti-anxiety drug (alprazolam), sedative-hypnotic drug (zolpidem), bronchodilator (albuterol), antibiotic (ciprofloxacin).

Drug-Disease Interaction:

 MEFENAMIC ACID+TIZANIDINE may have interactions with patients having peptic ulcers, bleeding disorders, asthma, fluid retention, gastrointestinal toxicity, rash, renal toxicity, thrombosis, anaemia, heart failure, liver toxicity, high blood pressure, platelet aggregation inhibition, and hyperkalemia (high potassium levels).

Safety Advice

ALCOHOL

• You are recommended to avoid alcohol consumption with MEFENAMIC ACID+TIZANIDINE as it may increase the risk of adverse effects.

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PREGNANCY

• MEFENAMIC ACID+TIZANIDINE belongs to pregnancy category C. Please consult your doctor before taking MEFENAMIC ACID+TIZANIDINE if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

• It is unknown whether MEFENAMIC ACID+TIZANIDINE is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. MEFENAMIC ACID+TIZANIDINE is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

DRIVING

• MEFENAMIC ACID+TIZANIDINE may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

LIVER

• Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

• Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.