PRODUCT DETAILS

About Dixmeta 50mg/400mg Tablet

DICLOFENAC+METAXALONE belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killers. DICLOFENAC+METAXALONE is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

DICLOFENAC+METAXALONE is a combination of two drugs namely: Diclofenac and Metaxalone. Diclofenac is a pain killer (NSAIDs) while Metaxalone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Metaxalone works by blocking the nerve impulses and pain sensations in the brain, thereby helping in maintaining muscle strength and relieving muscle spasms or stiffness. Together, DICLOFENAC+METAXALONE helps in relieving pain due to muscle spasms.

Take DICLOFENAC+METAXALONE with food. Do not chew, or break the tablet; swallow it as a whole with a glass of water.  You are advised to take DICLOFENAC+METAXALONE for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as stomach pain, nausea, vomiting, diarrhea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

DICLOFENAC+METAXALONE can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use DICLOFENAC+METAXALONE. DICLOFENAC+METAXALONE increases the chances of stomach ulcers and bleeding. To treat your condition effectually, continue taking DICLOFENAC+METAXALONE for as long as your doctor has prescribed. Do not take DICLOFENAC+METAXALONE if you are pregnant or breastfeeding unless prescribed. DICLOFENAC+METAXALONE causes drowsiness and dizziness, so drive with caution. DICLOFENAC+METAXALONE should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with DICLOFENAC+METAXALONE as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Dixmeta 50mg/400mg Tablet

Pain due to muscle spasm

Medicinal Benefits of Dixmeta 50mg/400mg Tablet

DICLOFENAC+METAXALONE is a combination of two drugs: Diclofenac and Metaxalone. Diclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug), and metaxalone is a skeletal muscle relaxant. DICLOFENAC+METAXALONE is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Metaxalone works on the centers of the spinal cord and brain, thereby helping in maintaining muscle strength and relieving muscle spasms or stiffness. Together, DICLOFENAC+METAXALONE helps in relieving pain due to muscle spasms.

Directions for Use

Take DICLOFENAC+METAXALONE with food. Do not chew, or break the tablet; swallow it as a whole with a glass of water. Based on your medical condition, your doctor will decide how long you need to take DICLOFENAC+METAXALONE.

Side Effects of Dixmeta 50mg/400mg Tablet

Like all medicines, DICLOFENAC+METAXALONE can also cause side effects, although not everybody experiences them. Stomach pain, nausea, vomiting, diarrhea, dizziness, and headache are the common side-effects of DICLOFENAC+METAXALONE. Please consult your doctor if you experience any of these side effects persistently.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

DICLOFENAC+METAXALONE can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use DICLOFENAC+METAXALONE. Do not take DICLOFENAC+METAXALONE if you are allergic to DICLOFENAC+METAXALONE, have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any pain killers or you have liver or kidney problems. Inform your doctor before taking DICLOFENAC+METAXALONE if you have had high blood pressure, heart problems, high cholesterol, diabetes, asthma, or liver and kidney problems. Do not take DICLOFENAC+METAXALONE if you are pregnant or breastfeeding unless prescribed. DICLOFENAC+METAXALONE causes drowsiness and dizziness, so drive only if you are alert. DICLOFENAC+METAXALONE should not be given to children as safety has not been established. Avoid consuming alcohol along with DICLOFENAC+METAXALONE as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking DICLOFENAC+METAXALONE and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAIDs for pain relief along with DICLOFENAC+METAXALONE unless prescribed. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug Interactions

Drug-Drug Interaction:

DICLOFENAC+METAXALONE may have interaction with ibuprofen, naproxen, aspirin, hydrocodone, acetaminophen, oxycodone, tramadol (used to relieve pain), hydrochlorothiazide (used to treat edema), lisinopril, metoprolol (used to treat high blood pressure), prednisone (used to reduce inflammation), rivaroxaban (used to prevent blood clots), zolpidem (used to induce sleepiness), diphenhydramine, cetirizine (used to treat allergy), gabapentin, clonazepam, pregabalin (used to treat fits),  duloxetine, escitalopram, sertraline (used to treat depression), diazepam, alprazolam (used to treat anxiety).

Drug-Disease Interaction:

 DICLOFENAC+METAXALONE may have interactions with anemia, asthma, fluid retention, gastrointestinal toxicity, rash, thrombosis (formation of clots), high blood pressure, hyperkalemia (high potassium levels), heart, kidney, and liver problems

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking DICLOFENAC+METAXALONE as it may increase drowsiness. It can also increase the risk of stomach bleeding.

PREGNANCY

Avoid taking DICLOFENAC+METAXALONE if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Consult your doctor before taking DICLOFENAC+METAXALONE; your doctor will decide whether DICLOFENAC+METAXALONE can be taken by breastfeeding mothers or not.

DRIVING

DICLOFENAC+METAXALONE causes drowsiness. Do not drive or operate machinery unless you are alert.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.