PRODUCT DETAILS

About Isonex 300mg Tablet

ISONIAZID belongs to the group of medicines called anti-tuberculosis primarily used to treat and prevent tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine, and bone marrow. ISONIAZID does not work against infections caused by the virus.

Uses of Isonex 300mg Tablet

Tuberculosis (TB)

Medicinal Benefits of Isonex 300mg Tablet

ISONIAZID contains Isoniazid, an antibiotic used to treat and prevent tuberculosis. ISONIAZID prevents the production of mycolic acids by bacteria that are essential for the formation of cell walls (protective coating). Also, ISONIAZID may combine with an enzyme that interferes with the cell metabolism of bacteria. Thereby, bacteria die without a cell wall and due to disruption in their metabolism.  Thus, it destroys the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis), and eliminates the infection.

Directions for Use

If you are prescribed ISONIAZID in oral form, swallow the whole tablet with a water glass. Take ISONIAZID on an empty stomach. Do not take ISONIAZID with food. Do not break, crush or chew it. ISONIAZID in injection form is injected into veins, muscles, chest or spine by a doctor or nurse. The ideal time to take an oral form of ISONIAZID is at least one hour before breakfast or snack or after two hours of a meal.

Side Effects of Isonex 300mg Tablet

• Fever
• Dizziness
• Nausea
• Stomach upset
• Loss of appetite
• Constipation
• Tiredness
• Numbness or tingling in the feet or hands

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

If you are known to be allergic to ISONIAZID or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking ISONIAZID. ISONIAZID may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking ISONIAZID. Avoid foods and drinks containing a high level of tyramine such as fermented foods, cheese, cured meat, soya, tuna, salmon, mackerel, wine, and beer while taking ISONIAZID as they might cause drug-drug interaction. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking ISONIAZID.

Drug Interactions

Drug-Drug Interaction:

 ISONIAZID may have interaction with anticonvulsants (carbamazepine, primidone, ethosuximide, phenytoin), an antidepressant (duloxetine, escitalopram), immunosuppressant (adalimumab), anti-asthma drugs (montelukast), vitamin (cholecalciferol), painkiller (acetaminophen), antibiotics (cycloserine, rifampicin), antianxiety drug (diazepam), medicines used to treat insomnia (triazolam), antifungals (ketoconazole, itraconazole), muscle relaxant (chlorzoxazone), bronchodilator (theophylline), medicines used to treat alcohol dependence (disulfiram), corticosteroids (prednisolone), antiparkinson drug (levodopa).

Drug-Disease Interaction:

If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking ISONIAZID.

Safety Advice

ALCOHOL

Avoid alcohol intake with ISONIAZID as it may increase the risk of liver damage. Please consult a doctor before consuming alcohol with ISONIAZID.

PREGNANCY

Please consult a doctor if you are pregnant. ISONIAZID is given to pregnant women only if the doctor thinks benefits outweigh risks.

BREAST FEEDING

ISONIAZID is excreted in breast milk. Please consult a doctor if you are a breastfeeding mother. ISONIAZID is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks

DRIVING

ISONIAZID may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking ISONIAZID.

LIVER

Take ISONIAZID with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

KIDNEY

Take ISONIAZID with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.