PRODUCT DETAILS

About Listril Plus Tablet

LISINOPRIL+HYDROCHLOROTHIAZIDE belongs to a class of medication called 'anti-hypertensive agents' prescribed alone or in combination with other drugs to lower the raised blood pressure. LISINOPRIL+HYDROCHLOROTHIAZIDE is also used to treat fluid retention (oedema) and kidney problems due to Type II diabetes in patients with high blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Uses of Listril Plus Tablet

Hypertension (high blood pressure)

Medicinal Benefits of Listril Plus Tablet

LISINOPRIL+HYDROCHLOROTHIAZIDE contains Lisinopril and hydrochlorothiazide. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and therefore helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, collectively, both help lower high blood pressure, reducing the chances of heart attack or stroke. However, LISINOPRIL+HYDROCHLOROTHIAZIDE does not cure high blood pressure (hypertension) but does help control it.  

Directions for Use

LISINOPRIL+HYDROCHLOROTHIAZIDE can be taken orally with or without food or as directed by your doctor. It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate. Dosage is based on your medical condition, age, and response to treatment.

Side Effects of Listril Plus Tablet

• Nausea
• Taste change
• Indigestion
• Stomach pain
• Diarrhoea
• Dizziness
• Decreased blood pressure
• Cough
  • Electrolyte imbalance

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

LISINOPRIL+HYDROCHLOROTHIAZIDE should not be given to the people with diabetes, impaired kidney function, if you are unable to urinate, pregnant women, or planning to get pregnant and breastfeeding women. LISINOPRIL+HYDROCHLOROTHIAZIDE may contraindicate in patients with low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (patients with nil urine output), and aortic stenosis (heart valve problem). LISINOPRIL+HYDROCHLOROTHIAZIDE can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking LISINOPRIL+HYDROCHLOROTHIAZIDE and breastfeeding. Do not consume alcohol with LISINOPRIL+HYDROCHLOROTHIAZIDE as it may increase the risk of low blood pressure. Avoid potassium supplements with LISINOPRIL+HYDROCHLOROTHIAZIDE as it may lead to high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while taking LISINOPRIL+HYDROCHLOROTHIAZIDE. Drink a lot of fluids as LISINOPRIL+HYDROCHLOROTHIAZIDE can cause dehydration, so to avoid unpleasant side-effects, increase the intake of fluids. LISINOPRIL+HYDROCHLOROTHIAZIDE is not recommended for children with severe kidney impairment. Inform your doctor before taking LISINOPRIL+HYDROCHLOROTHIAZIDE if you have low levels of potassium or sodium in your blood, glaucoma, narrowing (stenosis) of the kidney artery, high levels of calcium in your blood, kidney disease, liver disease. Before undergoing any surgery, inform the surgeon ahead of time that you are using LISINOPRIL+HYDROCHLOROTHIAZIDE. Inform your doctor, if you are already taking medicines such as high blood pressure medication (valsartan, telmisartan, irbesartan), Racecadotril, a medicine used to treat diarrhoea, Vildagliptin, a medicine used to treat diabetes.

Drug Interactions

Drug-Drug Interaction:

LISINOPRIL+HYDROCHLOROTHIAZIDE may interact with cholestyramine, colestipol (cholesterol-lowering medicines); insulin or oral diabetes medicine; lithium (used to major depressive disorder); NSAIDs (to treat pain and inflammation)--aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam. Racecadotril, a medicine used to treat diarrhoea; Vildagliptin, a medicine used to treat diabetes.

Drug-Disease Interaction:

LISINOPRIL+HYDROCHLOROTHIAZIDE should not be given to people with low blood pressure (hypotension), severe allergic reactions (angioedema), liver disease, or heart failure, gout, diabetes or impaired kidney function, patients with nil urine output (anuria), etc.

Safety Advice

ALCOHOL

• It is advised to avoid consuming alcohol with LISINOPRIL+HYDROCHLOROTHIAZIDE as it could lead to increased drowsiness or dizziness.

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PREGNANCY

• The use of LISINOPRIL+HYDROCHLOROTHIAZIDE or any ACE inhibitors (lisinopril) is usually contraindicated during the second and third trimester of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using LISINOPRIL+HYDROCHLOROTHIAZIDE.

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BREAST FEEDING

• Use of LISINOPRIL+HYDROCHLOROTHIAZIDE is not recommended during breastfeeding.

DRIVING

• Drive with caution, LISINOPRIL+HYDROCHLOROTHIAZIDE may cause blurry vision, and dizziness or weariness may occur.

LIVER

• LISINOPRIL+HYDROCHLOROTHIAZIDE to be taken with caution, especially in case of liver disease. The dose may have to be adjusted by your doctor.

KIDNEY

• LISINOPRIL+HYDROCHLOROTHIAZIDE to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor.