PRODUCT DETAILS

About Ributin Capsule

RIFABUTIN belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis in individuals dealing with human immunodeficiency virus (HIV) infection. Tuberculosis (TB) is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine, and bone marrow. HIV is a virus that weakens the immune system and increases the risk of TB infection. 

RIFABUTIN consists of a drug called 'Rifabutin' that comes into 'antimycobacterial'. It works by inactivating a bacterial RNA-polymerase, an enzyme that allows TB bacteria to make and replicate essential proteins. It destroys the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis), thus treating TB infection.

Uses of Ributin Capsule

Tuberculosis in patients infected HIV

Medicinal Benefits of Ributin Capsule

RIFABUTIN is indicated in patients dealing with TB caused by HIV infection to prevent or slow down the spread of TB infection. Persons who are living with HIV infection are at risk of developing TB. This disease can quickly progress in persons whose immune system is already weakened by the HIV infection, so RIFABUTIN helps to stop the growth and spread of bacteria responsible for causing and spreading infection. It does so by stopping the synthesis of a protein required by bacteria to grow and spread rapidly. 

Directions for Use

Take RIFABUTIN by oral route with or without food. Swallow RIFABUTIN as a whole; do not crush or chew the tablet. The dose and duration of RIFABUTIN can vary depending upon your condition, the weight of the person, and the severity of the infection. An individual can take RIFABUTIN with food if stomach upset happens. Please note that continue taking RIFABUTIN at spaced intervals until the prescribed amount is completed, even if symptoms go away. Stopping RIFABUTIN too early or missing doses may make the bacteria grow in the body, which may also result in the return of the infection and cause infection to be difficult to treat(drug-resistant).

Side Effects of Ributin Capsule

• Nausea (feeling sick)
• Drowsiness
• Dizziness
• Headache
• Sudden wheeziness, difficulty in breathing
• Weakness
• Fever/high temperature
• Pain in the chest
• Muscle pain 
• Skin rash
• Heartburn 
• Diarrhea
• Gas
• Numbness 

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug-Drug Interaction:

RIFABUTIN may have interaction with anti-HIV (saquinavir, ritonavir), pain killer (acetaminophen, hydrocodone), anti-depressant (duloxetine, bupropion), calcium channel blocker (diltiazem), anti-TB (ethambutol, pyrazinamide), and vitamins (ergocalciferol, cholecalciferol).

Safety Advice

DRIVING

RIFABUTIN may cause dizziness, drowsiness, numbness, and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

LIVER

Dose adjustment may be needed.

KIDNEY

Dose adjustment may be needed.