PRODUCT DETAILS

About Topcin TZ 200 mg/300 mg Tablet

OFLOXACIN+TINIDAZOLE is a combination of medicine called 'antibiotics' primarily used to treat various infections caused by bacteria & protozoans. OFLOXACIN+TINIDAZOLE is used to treat a wide variety of infections caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes, and protozoa. Examples of infection caused by protozoa include dysentery (inflammation of the colon) and malaria. 

OFLOXACIN+TINIDAZOLE is a combination of two antibiotics, namely: Ofloxacin and Tinidazole. Ofloxacin helps in treating and preventing a wide range of bacterial infections. It is bactericidal in nature that means it works by killing bacteria that cause infections. It inhibits bacterial cells' process, ultimately destroying the bacteria, thereby preventing the further spread of the infection. OFLOXACIN+TINIDAZOLE is a broad-spectrum antibiotic against most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria (that lives without oxygen). On the other hand, Tinidazole kills parasites and anaerobic bacteria responsible for causing infections. It works by damaging their genetic material called DNA. 

Uses of Topcin TZ 200 mg/300 mg Tablet

Bacterial infections, Protozoal infections

Medicinal Benefits of Topcin TZ 200 mg/300 mg Tablet

OFLOXACIN+TINIDAZOLE contains antibiotic Ofloxacin and Tinidazole, which helps treat and prevent a wide range of bacterial infections caused by most Gram-negative bacteria, many Gram-positive bacteria and some anaerobic bacteria (that lives without oxygen). It is bactericidal in nature and works by killing bacteria that cause infections by prevents the formation of their cell wall required for living. It also inhibits the repairing of bacterial cells. Altogether it kills the bacteria. OFLOXACIN+TINIDAZOLE has the advantage of good penetration in most deep tissues and body fluid. Hence, it is also suitable for the treatment of deep tissue and bone bacterial infections. 

Directions for Use

OFLOXACIN+TINIDAZOLE can be taken with or without food (excluding dairy products). OFLOXACIN+TINIDAZOLE should not be used unless prescribed by a doctor. Always take this medicine exactly as your doctor has told you. Check with your doctor if you are not sure.

Side Effects of Topcin TZ 200 mg/300 mg Tablet

• Nausea
• Vomiting
• Headache
• Headache
• Metallic taste 
• Stomach pain
• Loss of appetite
• Dryness in the mouth

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take OFLOXACIN+TINIDAZOLE if you are allergic or have had a severe reaction to ofloxacin or any other quinolone or fluoroquinolone antibiotics such as delafloxacin, gemifloxacin, levofloxacin, moxifloxacin, and ciprofloxacin. Taking OFLOXACIN+TINIDAZOLE may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, kidney disease, a joint or tendon disorder such as rheumatoid arthritis (an autoimmune condition of joints causing pain, swelling, and loss of function), seizures (fits), epilepsy or if you participate in regular physical activity. Taking OFLOXACIN+TINIDAZOLE may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Dairy products should be avoided along with OFLOXACIN+TINIDAZOLE. And also, exposure to sunlight should be avoided while taking OFLOXACIN+TINIDAZOLE as it may cause increased phototoxicity or photosensitivity. Patients with epilepsy and irregular heartbeat (QT prolongation) should tell their doctor before taking OFLOXACIN+TINIDAZOLE. 

Drug Interactions

Drug-Drug Interaction:

This medicine may have an interaction with blood thinners (aspirin, warfarin), antidepressants and antipsychotics (clozapine, olanzapine), caffeine, insulin or other anti-diabetic medications (chlorpropamide, glimepiride, glipizide, glyburide, metformin, tolazamide, and tolbutamide), medications for regulating irregular heartbeat (amiodarone, disopyramide, procainamide, quinidine), pain killers (ibuprofen, naproxen). Take OFLOXACIN+TINIDAZOLE either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product with calcium, magnesium, aluminium, iron, zinc, antiulcer agent (sucralfate) or anti-HIV drug (didanosine).

Drug-Disease Interaction:

Inform your doctor if you have or have ever had tendon rupture, musculoskeletal problem (myopathy, rhabdomyolysis), kidney/heart/lung transplant,  low blood potassium (hypokalemia), kidney disease, rheumatoid arthritis, seizures (fits), epilepsy or any other neurological disorder if you participate in regular physical activity before starting OFLOXACIN+TINIDAZOLE.

Safety Advice

ALCOHOL

Alcohol is not known to cause any unpleasant side effects if taken along with OFLOXACIN+TINIDAZOLE. But intake of alcohol with OFLOXACIN+TINIDAZOLE may damage your liver. So intake of OFLOXACIN+TINIDAZOLE should be avoided with OFLOXACIN+TINIDAZOLE.

PREGNANCY

OFLOXACIN+TINIDAZOLE is a pregnancy Category C medicine. It is not known whether OFLOXACIN+TINIDAZOLE will affect pregnant women or fetus or not. Hence, the intake of OFLOXACIN+TINIDAZOLE should be avoided if you are pregnant or planning to become pregnant as it may harm the baby.

BREAST FEEDING

OFLOXACIN+TINIDAZOLE is excreted in human milk. But the amount of OFLOXACIN+TINIDAZOLE absorbed by the nursing infant is unknown. So, it should not be taken while breastfeeding.

DRIVING

OFLOXACIN+TINIDAZOLE can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

LIVER

OFLOXACIN+TINIDAZOLE to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-colored urine, yellowing of or skin/eye.

KIDNEY

OFLOXACIN+TINIDAZOLE to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.